The No. 9 Notre Dame Fighting Irish (7-2) visit the No. 23 Pittsburgh Panthers (7-2) at Acrisure Stadium on Saturday, November 15, 2025.
The Fighting Irish are double-digit favorites (currently -12.5) in their game versus the Panthers, with the over/under being 54.5 points. (On the moneyline, the Fighting Irish are -448 and the Panthers are +347.)
Keep reading for our betting primer for this this contest between the Fighting Irish and the Panthers, and discover all of our predictions here, too!
To Cover the Spread
Bet $20, Payout $38.35
Notre Dame -12.5 vs. Pittsburgh
Notre Dame vs. Pittsburgh betting lines
- Spread favorite: Fighting Irish (-12.5)
- Moneyline: Fighting Irish (-448), Panthers (+347)
- Total: 54.5 points
- TV Channel: ACC Network
- Live Stream: Fubo
Notre Dame vs. Pittsburgh betting info and stats
- Notre Dame has a 4-5-0 record against the spread this season. Notre Dame has covered the spread three times in games it was the favorite by at least 12.5 points (a 3-2 ATS record). Notre Dame has won seven of its nine games played when favored on the moneyline this season. Pittsburgh has won seven games against the spread this season (7-2-0). Pittsburgh has played a game as an underdog on the moneyline two times this season, and it split the two games.
Notre Dame vs. Pittsburgh recent stats and trends
Notre Dame Fighting Irish
- Notre Dame has covered the spread once in its last three matchups while putting together a 3-0 record straight-up in those games.
- The final combined score of the past three Notre Dame games surpassed the set total one time.
- Notre Dame’s past three outings have ended with an average of 57.2 points scored. That’s 2.7 more points than this contest’s over/under.
Pittsburgh Panthers
- Pittsburgh has covered the spread in each of its past three matchups, while going 3-0 overall.
- Pittsburgh and its opponents have combined to hit the over two times in those games.
- Pittsburgh’s last three games have ended with an average of 53.2 points scored. That’s 1.3 fewer points than this contest’s over/under.
Notre Dame vs. Pittsburgh key players
Notre Dame Fighting Irish
- CJ Carr has 2,275 yards passing for Notre Dame, completing 67.6% of his passes and recording 19 touchdowns and four interceptions this season.
- The team’s top rusher, Jeremiyah Love, has carried the ball 154 times for 988 yards (109.8 per game), scoring 13 times. He’s also caught 24 passes for 254 yards and three touchdowns.
- Jadarian Price has carried the ball 95 times for 568 yards (63.1 per game) and nine touchdowns.
- Jordan Faison’s 545 yards as a receiver pace the team. He’s been targeted 54 times and has totaled 43 catches and three touchdowns.
- Malachi Fields has put together a 497-yard season so far with three touchdowns, hauling in 25 passes on 47 targets.
- Eli Raridon has been the target of 31 passes and racked up 24 receptions for 406 yards, an average of 58.0 yards per contest.
- Boubacar Traore leads the team with 5.5 sacks, and also has 6.0 TFL and 29 tackles.
- Notre Dame’s leading tackler, Drayk Bowen, has 44 tackles, 1.0 TFL, and two sacks this year.
- Leonard Moore leads the team with three interceptions, while also recording 20 tackles and three passes defended.
Pittsburgh Panthers
- Mason Heintschel has thrown for 1,550 yards on 64.1% passing while tossing 12 touchdown passes with five interceptions this season. He’s also run for 143 yards with one score.
- Ja’Kyrian Turner has rushed 88 times for 401 yards, with six touchdowns.
- Desmond Reid has taken 55 carries and totaled 266 yards with two touchdowns while also gaining 254 yards through the air with two touchdowns.
- Raphael Williams’ 565 receiving yards (62.8 yards per game) are best on his team. He has 37 receptions on 59 targets with six touchdowns.
- Kenny Johnson has totaled 536 receiving yards (59.6 yards per game) and four touchdowns on 36 receptions.
- Cataurus Hicks’ 33 targets have resulted in 19 catches for 353 yards and four touchdowns.
- Jimmy Scott paces the team with 3.5 sacks, and also has 4.0 TFL and 15 tackles.
- Braylan Lovelace, Pittsburgh’s top tackler, has 54 tackles, 3.0 TFL, and one interception this year.
- Kyle Louis has picked off a team-high two passes. He also has 50 tackles, 5.0 TFL, two sacks, and two passes defended to his name.
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