The No. 4 Alabama Crimson Tide (6-1) and the South Carolina Gamecocks (3-4) square off on Saturday, October 25, 2025 at Williams-Brice Stadium in a battle of SEC opponents.

The Crimson Tide are expected to win by at least two scores (currently -11.5) versus the Gamecocks. The over/under for this game is 48 points.

Keep reading to check out our betting primer for this this contest between the Crimson Tide and the Gamecocks, and discover all of our expert predictions here, too!

Alabama vs. South Carolina betting lines

• Spread favorite: Crimson Tide (-11.5)
• Moneyline: Crimson Tide (-442), Gamecocks (+343)
• Total: 48 points
• TV Channel: ABC (WLS – Chicago, IL)
• Live Stream: Fubo

Alabama vs. South Carolina betting info and stats

Alabama, through seven games with a spread this season, has gone 5-2-0 against the spread. Alabama has a 3-1 ATS record when the favorite by at least 11.5 points. In six games as a moneyline favorite, Alabama has gone 5-1. South Carolina has three wins against the spread this season (3-4-0). South Carolina has been an underdog on the moneyline three times so far this season, losing each game.

Alabama vs. South Carolina recent stats and trends

Alabama Crimson Tide

• Alabama has covered the spread twice in its past three matchups while putting up a 3-0 record straight-up in those games.
• Alabama and its opponents did not combine to hit the over in any of those games.
• The last three Alabama games averaged 56.5 total points, 8.5 more points than this matchup’s over/under.

South Carolina Gamecocks

• South Carolina has covered the spread once in its last three matchups while putting up a 3-0 record straight-up in those games.
• South Carolina and its opponents have combined to hit the over one time in those games.
• South Carolina’s last three outings have ended with an average of 44.7 points scored. That’s 3.3 fewer points than this contest’s over/under.

Alabama vs. South Carolina key players

Alabama Crimson Tide

• Ty Simpson has recorded 1,931 yards (275.9 ypg) on 153-of-218 passing with 18 touchdowns compared to one interception this season.
• Jamarion Miller has 282 rushing yards on 70 carries with two touchdowns.
• Kevin Riley has carried the ball 47 times for 181 yards (25.9 per game) while also racking up 139 yards through the air, scoring one time.
• Germie Bernard’s leads his squad with 472 yards as a receiver. He’s racked up that yardage on 33 catches (out of 48 targets) and scored five touchdowns.
• Ryan Williams has put up a 423-yard season so far with three touchdowns, hauling in 26 passes on 38 targets.
• Isaiah Horton has been the target of 29 passes and hauled in 22 grabs for 272 yards, an average of 38.9 yards per contest. He’s found the end zone five times through the air this season.
• Yhonzae Pierre paces the team with 4.0 sacks, and also has 6.0 TFL and 24 tackles.
• Alabama’s top-tackler, Justin Jefferson, has 40 tackles, 1.0 TFL, one sack, and one interception this year.
• Bray Hubbard has picked off a team-leading three passes. He also has 31 tackles, 1.0 TFL, and three passes defended to his name.

South Carolina Gamecocks

• LaNorris Sellers has compiled 1,134 yards (162.0 yards per game) while completing 64.7% of his passes and recording five touchdown passes with two interceptions this season. He’s also rushed for 108 yards with one touchdown.
• Rahsul Faison is his team’s leading rusher with 64 carries for 281 yards, or 40.1 per game. He’s found paydirt three times on the ground, as well.
• Matthew Fuller has piled up 151 yards (on 38 attempts) with two touchdowns.
• Vandrevius Jacobs paces his squad with 343 receiving yards on 21 receptions with two touchdowns.
• Nyck Harbor has caught 17 passes and compiled 278 receiving yards (39.7 per game) with two touchdowns.
• Donovan Murphree’s seven grabs (on 14 targets) have netted him 118 yards (23.6 ypg).
• Bryan Thomas Jr. paces the team with 4.0 sacks, and also has 5.0 TFL and 21 tackles.
• DQ Smith is the team’s leading tackler this year. He’s racked up 35 tackles and one interception.
• Peyton Williams leads the team with two interceptions, while also putting up 26 tackles and two passes defended.