The Ohio Bobcats (1-2) play an FCS opponent, the Gardner-Webb Runnin’ Bulldogs (2-1), on Saturday, September 20, 2025 at Frank Solich Field at Peden Stadium.

The Bobcats are very heavy favorites (currently -29.5) in their matchup against the Runnin’ Bulldogs, with the over/under being 55.5 points. (In terms of the moneyline, the Bobcats are -8333 and the Runnin’ Bulldogs are +2275.)

Keep reading for our betting preview for this this contest between the Bobcats and the Runnin’ Bulldogs, and uncover all of our expert predictions here, too!

Ohio vs. Gardner-Webb betting lines

• Spread favorite: Bobcats (-29.5)
• Moneyline: Bobcats (-8333), Runnin’ Bulldogs (+2275)
• Total: 55.5 points

Ohio vs. Gardner-Webb betting info and stats

Ohio is 3-0-0 against the spread so far this season. Ohio has not been the moneyline favorite so far this season. Gardner-Webb has won twice against the spread this season (2-1-0). When Gardner-Webb is an underdog of 29.5 points or more, it has not yet covered the spread. This will be the second game this year Gardner-Webb is the moneyline underdog. The Runnin’ Bulldogs won the first one.

Ohio vs. Gardner-Webb key players

Ohio Bobcats

• Parker Navarro has thrown for 580 yards, completing 65.3% of his passes and tossing five touchdowns and three interceptions this season. He’s also run for 183 yards (61.0 ypg) on 32 carries with one rushing touchdown.
• Sieh Bangura has been handed the ball 48 times this year and racked up 176 yards (58.7 per game) with one touchdown.
• Chase Hendricks’ team-leading 312 yards as a receiver have come on 20 catches (out of 26 targets) with two touchdowns.
• Max Rodarte has put together an 87-yard season so far, reeling in six passes on 11 targets.
• Eian Pugh has been the target of four passes and compiled four catches for 51 yards, an average of 25.5 yards per contest.
• Anas Luqman has 2.0 sacks to lead the team, and also has 3.0 TFL and nine tackles.
• Ohio’s tackle leader, Adonis Williams Jr., has 23 tackles and 1.0 TFL this year.
• Cameron Hollobaugh has a team-high one interception to go along with 11 tackles and one pass defended.

Gardner-Webb Runnin’ Bulldogs

• Nate Hampton has thrown for 514 yards on 31-of-61 passing with five touchdowns and zero interceptions this season. He has chipped on the ground, as well, with 157 yards and four rushing touchdowns.
• The team’s top rusher, Quasean Holmes, has carried the ball 44 times for 254 yards (84.7 per game) with one touchdown.
• Chris Lofton’s 248 receiving yards (82.7 yards per game) are best on his team. He has 11 receptions on 13 targets with one touchdown.
• Anthony Lowe has put together a 197-yard season so far with three touchdowns. He’s caught 17 passes on 20 targets.
• Caleb Borders has racked up 117 reciving yards (39.0 ypg) and two touchdowns this season.
• Robert Holtz leads the team with 2.0 sacks, and also has 11 tackles and one pass defended.
• Jecari Bryson, Gardner-Webb’s top tackler, has 11 tackles and one pass defended this year.
• Josiah Harris has picked off a team-leading one pass. He also has 11 tackles and one pass defended to his name.