The Ohio Bobcats (7-4) hit the road for a MAC showdown against the Buffalo Bulls (5-6) on Friday, November 28, 2025 at UB Stadium.

The Bobcats are favored, but by less than a touchdown (-6.5), versus the Bulls. The over/under for this matchup is 44.5 points.

Read on for our betting primer for this this contest between the Bobcats and the Bulls, and discover all of our expert picks here, too!

Ohio vs. Buffalo betting lines

• Spread favorite: Bobcats (-6.5)
• Moneyline: Bobcats (-252), Bulls (+204)
• Total: 44.5 points
• TV Channel: ESPN U
• Live Stream: Fubo

Ohio vs. Buffalo betting info and stats

Ohio has won six games against the spread so far this season (6-5-0). Ohio is 2-4 ATS when the favorite by at least 6.5 points. Ohio has recorded a 6-1 record in the seven games this season it has been moneyline favorites. Buffalo, in 11 games with a set spread so far this season, is 3-7-1 against the spread. When Buffalo is an underdog by 6.5 points or more, it has gone 1-0 ATS. Buffalo’s record in games it’ve played as the underdog this year is 1-4.

Ohio vs. Buffalo recent stats and trends

Ohio Bobcats

• Ohio is 1-2 against the spread and 2-1 overall during its last three matchups.
• One time in those three games, the final combined score surpassed the set total.
• The past three Ohio games averaged 5.7 more points (50.2) than this matchup’s point total.

Buffalo Bulls

• Buffalo has covered the spread once in its past three contests while putting together a 2-1 record straight-up in those games.
• Twice in those three games, the final combined score has exceeded the set total.
• The last three Buffalo games averaged 42.2 total points, 2.3 fewer points than this matchup’s over/under.

Ohio vs. Buffalo key players

Ohio Bobcats

• Parker Navarro leads Ohio with 2,085 yards (189.5 ypg) on 167-of-265 passing with 12 touchdowns and nine interceptions this season. He also has 722 rushing yards on 131 carries while scoring seven touchdowns on the ground.
• Sieh Bangura has racked up 1,123 yards on 199 carries while finding paydirt 13 times.
• Chase Hendricks’ team-high 858 yards as a receiver have come on 62 catches (out of 98 targets) with six touchdowns.
• Rodney Harris II has grabbed 25 passes while averaging 36.4 yards per game and scoring two touchdowns.
• Mason Williams has hauled in 23 grabs for 253 yards, an average of 23.0 yards per game. He’s scored two times as a receiver this season.
• Jay Crable has 5.0 sacks to pace the team, and also has 6.0 TFL and 21 tackles.
• Jalen Thomeson, Ohio’s top tackler, has 58 tackles, 3.0 TFL, and one interception this year.
• Mike Mack has picked off a team-high two passes. He also has 27 tackles, 1.0 TFL, and two passes defended to his name.

Buffalo Bulls

• Ta’Quan Roberson has racked up 2,250 yards on 57.6% passing while collecting 15 touchdown passes with 11 interceptions this season. He’s also rushed for 121 yards with two scores.
• The team’s top rusher, Al-Jay Henderson, has carried the ball 177 times for 724 yards (65.8 per game) with five touchdowns. He’s also caught 25 passes for 181 yards and one touchdown.
• Lamar Sperling has run for 221 yards across 37 carries, scoring one touchdown.
• Nik McMillan’s 853 receiving yards (77.5 yards per game) are a team high. He has 56 catches on 91 targets with three touchdowns.
• Victor Snow has 58 receptions (on 83 targets) for a total of 733 yards (66.6 yards per game) and eight touchdowns this year.
• Jasaiah Gathings has racked up 380 reciving yards (38.0 ypg) and two touchdowns this season.
• Junior Poyser has 5.0 sacks to pace the team, and also has 4.0 TFL and 23 tackles.
• Khalil Murdock, Buffalo’s top tackler, has 95 tackles, 7.0 TFL, and 4.5 sacks this year.
• Mitchell Gonser has a team-leading two interceptions to go along with 45 tackles, 2.0 TFL, one sack, and two passes defended.