The Charlotte 49ers (0-1) host the North Carolina Tar Heels (0-1) at Jerry Richardson Stadium on Saturday, September 6, 2025.

The Tar Heels are expected to come out on top by at least two touchdowns (currently -14.5) against the 49ers. The over/under for this matchup is 49.5 points.

Keep reading for our preview for this this game between the Tar Heels and the 49ers, and discover all of our predictions here, too!

North Carolina vs. Charlotte betting lines

• Spread favorite: Tar Heels (-14.5)
• Moneyline: Tar Heels (-667), 49ers (+478)
• Total: 49.5 points

North Carolina vs. Charlotte betting info and stats

North Carolina, through one game with a spread so far this season, has gone 0-1-0 against the spread. North Carolina has yet to play a game as a moneyline favorite. Charlotte has not won a game against the spread this season (0-1-0). Charlotte has played a game as an underdog on the moneyline once this season, and failed to pick up the victory.

North Carolina vs. Charlotte key players

North Carolina Tar Heels

• Jacolby Criswell’s previous season stat line: 2,459 passing yards (189.2 per game), 186-for-320 (58.1%), 15 touchdowns and six picks.
• Last season Omarion Hampton picked up 1,660 rushing yards (138.3 per game) and 15 touchdowns. In the receiving game, he made 38 catches for 373 yards and two scores.
• Davion Gause ran for 326 yards on 67 carries (27.2 yards per game), with four rushing touchdowns last year.
• In the previous year, J.J. Jones grabbed 36 passes (on 65 targets) for 582 yards (44.8 per game). He also found the end zone six times.
• John Copenhaver amassed 414 yards on 40 grabs with four touchdowns. He was targeted 58 times, and averaged 31.8 receiving yards per game.
• Beau Atkinson did his thing last season with a huge stat line of 7.5 sacks, 11 TFL and 35 tackles.
• Antavious Lane was a wrecking ball on the field, collecting 78 tackles, two TFL, and one sack last year.
• Marcus Allen intercepted two passes last year while also totaling 36 tackles, one TFL, and two passes defended.

Charlotte 49ers

• Deshawn Purdie averaged 150.2 passing yards per contest and tossed 10 touchdowns last season.
• Hahsaun Wilson averaged 46.6 rushing yards and collected seven rushing touchdowns.
• Last season Cartevious Norton rushed for 525 yards. He also scored seven total touchdowns.
• O’Mega Blake averaged 66.3 receiving yards and collected nine receiving touchdowns over the course of the 2024 season.
• Sean Brown caught 35 passes last season on his way to 470 yards and one receiving touchdown.
• Jairus Mack averaged 38 receiving yards per game on 2.7 targets per game a season ago.
• Last year Chantz Williams racked up four sacks, four TFL and 14 tackles.
• Reid Williford put together a great stat line last year, accruing 65 tackles, four TFL, and two sacks.
• Dontae Balfour racked up two interceptions in addition to 42 tackles, one TFL, and two passes defended a year ago.