Big Ten opponents match up when the No. 25 Michigan Wolverines (5-2) and the Michigan State Spartans (3-4) play on Saturday, October 25, 2025 at Spartan Stadium.

The Wolverines are very heavy favorites (currently -14) in their game against the Spartans, with the over/under at 47.5 points. (On the moneyline, the Wolverines are -578 and the Spartans are +425.)

Keep reading to check out our preview for this this matchup between the Wolverines and the Spartans, and discover all of our predictions here, too!

Michigan vs. Michigan State betting lines

• Spread favorite: Wolverines (-14)
• Moneyline: Wolverines (-578), Spartans (+425)
• Total: 47.5 points
• TV Channel: NBC (WBGH-Binghamton, NY)
• Live Stream: Fubo

Michigan vs. Michigan State betting info and stats

Michigan, through seven games with a spread so far this season, is 3-4-0 against the spread. Michigan has covered the spread once when the favorite by at least 14 points (a 1-2 ATS record). Michigan has been moneyline favorites for five games this season, and it has put together a 5-0 record in those matchups. Michigan State has three wins against the spread this season (3-4-0). In the two games Michigan State has been an underdog by at least 14 points this season, it has covered the spread both times. This is the fourth time this year Michigan State is the moneyline underdog, and have lost each such contest.

Michigan vs. Michigan State recent stats and trends

Michigan Wolverines

• Michigan is 1-2 against the spread over its last three games, and has a 2-1 straight-up record in those contests.
• Michigan and its opponents did not combine to hit the over in any of those games.
• The last three Michigan games averaged 50.0 total points, 2.5 more points than this matchup’s over/under.

Michigan State Spartans

• Michigan State has covered the spread twice in its past three contests while putting up a 2-1 record straight-up in those games.
• Michigan State and its opponents have combined to hit the over in two of those games.
• The past three Michigan State games averaged 2.3 more points (49.8) than this matchup’s over/under.

Michigan vs. Michigan State key players

Michigan Wolverines

• Bryce Underwood has thrown for 1,440 yards (205.7 ypg) to lead Michigan, completing 62.4% of his passes and collecting seven touchdown passes compared to two interceptions this season. He’s also figured in the ground game with 202 rushing yards on 39 carries with three rushing touchdowns.
• Justice Haynes has carried the ball 95 times for a team-high 705 yards on the ground and has found the end zone eight times as a runner.
• Jordan Marshall has carried the ball 84 times for 434 yards (62.0 per game) and four touchdowns.
• Donaven McCulley has hauled in 24 receptions for 369 yards (52.7 yards per game) to lead the team so far this season. He’s found the end zone two times as a receiver.
• Andrew Marsh has caught 18 passes for 297 yards (59.4 yards per game) and two touchdowns this year.
• Semaj Morgan has been the target of 31 passes and hauled in 19 receptions for 214 yards, an average of 30.6 yards per contest. He’s found the end zone one time through the air this season.
• Derrick Moore has collected 4.5 sacks to lead the team, while also picking up 3.0 TFL and 12 tackles.
• Jimmy Rolder, Michigan’s leading tackler, has 32 tackles, 2.0 TFL, one sack, and one interception this year.
• Cole Sullivan has picked off a team-leading three passes. He also has 19 tackles, 4.0 TFL, two sacks, and three passes defended to his name.

Michigan State Spartans

• Aidan Chiles has thrown for 1,262 yards (180.3 ypg) to lead Michigan State, completing 65.1% of his passes and tossing 10 touchdown passes and three interceptions this season. He is also a playmaker on the ground, racking up 234 yards (33.4 ypg) on 66 carries with five touchdowns.
• Makhi Frazier has rushed for 384 yards on 94 carries so far this year while scoring two times on the ground.
• Omari Kelly has hauled in 406 receiving yards on 27 catches to pace his squad so far this season while scoring one touchdown as a receiver.
• Nick Marsh has put together a 404-yard season so far with five touchdowns. He’s caught 36 passes on 58 targets.
• Chrishon McCray’s 24 targets have resulted in 13 receptions for 207 yards and one touchdown.
• Malik Spencer has collected 2.0 sacks to pace the team, while also recording 3.0 TFL and 29 tackles.
• So far Jordan Hall leads the team in both tackles and interceptions. He has racked up 49 tackles, 3.0 TFL, two sacks, and one interception this season.