The No. 3 LSU Tigers (3-0) face an FCS opponent, the SE Louisiana Lions (2-1), on Saturday, September 20, 2025 at Tiger Stadium.
The Lions are expected to lose by at least two touchdowns (currently +48.5) versus the Tigers (with an over/under of 61 points).
Keep reading to check out our betting primer for this this contest between the Tigers and the Lions, and discover all of our betting picks here, too!
To Cover the Spread
Bet $20, Payout $37.09
LSU -48.5 vs. SE Louisiana
LSU vs. SE Louisiana betting lines
- Spread favorite: Tigers (-48.5)
- Moneyline: Tigers (), Lions ()
- Total: 61 points
- TV Channel: SEC Network
- Live Stream: Fubo
LSU vs. SE Louisiana betting info and stats
- LSU, in three games with a spread this season, is 2-1-0 against the spread. LSU won both of the games it has played when favored on the moneyline this season. SE Louisiana, through three games with a set spread so far this season, is 2-1-0 against the spread. This is the second game this year SE Louisiana is an underdog on the moneyline. The Lions lost the first one.
LSU vs. SE Louisiana key players
LSU Tigers
- Garrett Nussmeier has thrown for 687 yards (229.0 ypg) to lead LSU, completing 65.1% of his passes and tossing three touchdown passes compared to two interceptions this season.
- Caden Durham has carried the ball 45 times for a team-high 196 yards on the ground and has found the end zone two times.
- Zavion Thomas has been handed the ball nine times this year and racked up 80 yards (40.0 per game). He’s also helped out in the pass game with nine grabs for 89 yards and one touchdown.
- Aaron Anderson has hauled in 18 catches for 247 yards (82.3 yards per game) to lead the team so far this season. .
- Barion Brown has reeled in 15 passes while averaging 48.3 yards per game.
- Bauer Sharp has been the target of 15 passes and compiled nine catches for 97 yards, an average of 32.3 yards per contest.
- Harold Perkins has racked up 1.0 sack to pace the team, while also recording 1.0 TFL and 13 tackles.
- LSU’s leading tackler, West Weeks, has 24 tackles, 1.0 TFL, and 0.5 sacks this year.
- Dashawn Spears leads the team with two interceptions, while also recording two passes defended.
SE Louisiana Lions
- Carson Camp leads SE Louisiana with 442 yards on 37-of-59 passing with three touchdowns compared to two interceptions this season. He has chipped in with 46 rushing yards (15.3 ypg) on 22 carries.
- Kyle Lowe is his team’s leading rusher with 23 carries for 145 yards, or 48.3 per game. He’s found the end zone three times on the ground, as well.
- Jaedon Henry has six receptions for 98 yards (32.7 per game) so far while also carrying the ball 26 times for 130 yards and two scores.
- Jaylon Domingeaux’s 152 receiving yards (50.7 yards per game) are a team high. He has 10 catches on 12 targets with three touchdowns.
- Tristan Goodly has totaled 104 receiving yards (52.0 yards per game) and one touchdown on six receptions.
- Rowan Briggs has 3.0 sacks to lead the team, and also has 2.0 TFL and five tackles.
- Ian Goodly is the team’s top-tackler this year. He’s totaled eight tackles.
- Shakespeare Louis has picked off a team-leading one pass. He also has eight tackles to his name.
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