The No. 25 Houston Cougars (8-2) square off against a conference opponent when they host the TCU Horned Frogs (6-4) on Saturday, November 22, 2025 at TDECU Stadium in a Big 12 clash.

The Cougars are favored, but by less than a field goal (-1.5), against the Horned Frogs. The over/under for this game is 55 points.

Read on for our betting preview for this this contest between the Cougars and the Horned Frogs, and find all of our predictions here, too!

Houston vs. TCU betting lines

• Spread favorite: Cougars (-1.5)
• Moneyline: Cougars (-121), Horned Frogs (+101)
• Total: 55 points
• TV Channel: FOX Net (Minot-Bismarck, ND)
• Live Stream: Fubo

Houston vs. TCU betting info and stats

Houston has seven wins against the spread this season (7-3-0). Houston has covered the spread five times when it has played as the favorite by at least 1.5 points (a 5-2 ATS record). Houston has been listed as moneyline favorites seven times this season, and has recorded a 6-1 record in those matchups. TCU has four wins against the spread in 10 opportunities so far this season (4-5-1). When TCU is an underdog of 1.5 points or more, it has not yet covered the spread. TCU has been listed as an underdog on the moneyline two times so far this season, and it lost both games.

Houston vs. TCU recent stats and trends

Houston Cougars

• Houston is 2-1 against the spread over its last three games, and has a 2-1 straight-up record in those contests.
• Twice in those three games, the final combined score has gone over the set total.
• The last three Houston games averaged 47.5 total points, 7.5 fewer points than this matchup’s over/under.

TCU Horned Frogs

• TCU has not covered a spread (0-3) while going 2-1 overall over its past three games.
• TCU and its opponents have hit the over in one of those games.
• The last three TCU games averaged 54.7 total points, 0.3 fewer points than this matchup’s point total.

Houston vs. TCU key players

Houston Cougars

• Conner Weigman has been a dual threat for Houston so far this season. He has 2,113 passing yards, completing 64.9% of his passes and recording 18 touchdown passes and seven interceptions this season. He’s rushed for 412 yards (41.2 ypg) on 120 carries with nine rushing touchdowns.
• Dean Connors has 725 rushing yards on 158 carries with four touchdowns. He’s also added 23 catches for 173 yards (17.3 per game) and two touchdowns through the air.
• Amare Thomas’ leads his squad with 737 yards as a receiver. He’s racked up that yardage on 45 receptions (out of 69 targets) and scored eight touchdowns.
• Tanner Koziol has hauled in 56 receptions totaling 570 yards, finding the end zone five times as a receiver so far this campaign.
• Stephon Johnson Jr. has been the target of 25 passes and racked up 13 catches for 275 yards, an average of 45.8 yards per contest. He’s found the end zone two times through the air this season.
• Eddie Walls III has 5.5 sacks to lead the team, and also has 5.0 TFL and 30 tackles.
• Jalen Garner, Houston’s leading tackler, has 43 tackles, 1.0 TFL, and two sacks this year.
• Latreveon McCutchin has a team-leading two interceptions to go along with 28 tackles, 1.0 TFL, one sack, and two passes defended.

TCU Horned Frogs

• Josh Hoover leads TCU with 2,873 yards on 229-of-358 passing with 23 touchdowns compared to 10 interceptions this season.
• Kevorian Barnes is his team’s leading rusher with 97 carries for 443 yards, or 63.3 per game. He’s found paydirt three times on the ground, as well.
• Trent Battle has run for 334 yards across 60 carries, scoring six touchdowns.
• Eric McAlister has hauled in 941 receiving yards on 52 catches to pace his team so far this season while scoring eight touchdowns as a receiver.
• Jordan Dwyer has collected 621 receiving yards (62.1 yards per game) and four touchdowns on 48 receptions.
• Joseph Manjack IV has racked up 397 reciving yards (49.6 ypg) and two touchdowns this season.
• Kaleb Elarms-Orr leads the team with 4.0 sacks. He’s also the team’s tackle leader, and has amassed 6.0 TFL and 73 tackles.
• Bud Clark has a team-high four interceptions to go along with 39 tackles, 1.0 TFL, one sack, and four passes defended.