Astros vs. Angels Betting Lines, Odds, & Player Matchups September 28, 2025

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Data Skrive

The Houston Astros (85-75) and the Los Angeles Angels (72-88) are looking for another strong showing from batters when the teams match up on Sunday at 3:07 p.m. ET at Angel Stadium. Christian Walker is currently on a two-game home run streak for the favored Astros (-143), and Mike Trout has also hit home runs in two games in a row for the underdog Angels (+121). Los Angeles has Samuel Aldegheri projected to start, while Houston has not named a starter.

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Betting Odds

Astros to win vs Angels -143

Bet $20, Payout $33.99

Astros vs. Angels betting lines

  • Favorite: Astros (-143)
  • Underdog: Angels (+121)
  • Over/under: 9

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros are 53-50 in games they were favored on the moneyline (winning 51.5% of those games).
  • Houston has a 22-19 record (winning 53.7% of its games) when it has played as moneyline favorites of -143 or shorter.
  • Based on this game’s moneyline, the Astros’ implied win probability is 58.8%.
  • Houston has combined with opponents to go over the total 72 times this season for a 72-81-7 record against the over/under.
  • The Astros have covered 49.4% of their games this season, going 79-81-0 against the spread.

Astros hitting info

  • Jose Altuve has launched a team-high 26 home runs.
  • Altuve ranks 42nd in homers and 60th in RBI among all batters in MLB.
  • Jeremy Pena is hitting .304 to pace his team.
  • Pena currently ranks 111th in homers and 117th in RBI in the bigs.
  • Yainer Diaz is hitting .255 with 25 doubles, a triple, 19 home runs and 20 walks.
  • Carlos Correa is hitting .276 with 29 doubles, 13 home runs and 45 walks.
  • Correa brings a three-game hitting streak into this game. In his last five games he is hitting .294 with two doubles, four walks and two RBIs.

Astros pitching rankings

  • The Astros pitching staff leads MLB with a collective 9.4 strikeouts per nine innings.
  • Houston’s 3.91 team ERA ranks 14th among all MLB pitching staffs.
  • Astros pitchers combine for the No. 8 WHIP in MLB (1.230).
  • The Astros give up the 21st-fewest home runs in baseball (198 total, 1.2 per game).
  • Houston struck out four Angels batters while giving up eight hits in a 4-3 loss in its last game.

Angels betting info, hitting leaders, & pitching

Angels betting info

  • This season, the Angels have been the underdog 121 times and won 53, or 43.8%, of those games.
  • This season, Los Angeles has won 33 of its 77 games, or 42.9%, when it’s the underdog by at least +121 on the moneyline.
  • Bookmakers have implied with the moneyline set for this matchup that the Angels have a 45.2% chance to win.
  • So far this season, Los Angeles and its opponents have hit the over in 85 of its 160 games with a total.
  • The Angels have an ATS record of 84-76-0 in 160 games with a spread this season.

Angels hitting info

  • Taylor Ward leads Los Angeles in runs batted in with 103 and has a batting average of .227.
  • In all of MLB, Ward is 10th in home runs and 11th in RBI.
  • Nolan Schanuel leads Los Angeles in batting with a .264 average while slugging 12 homers and driving in 53 runs.
  • Schanuel ranks 175th overall in homers and 153rd in RBI this season.
  • Jo Adell’s 37 home runs lead all Los Angeles hitters, and he’s slugging .486.
  • Trout has collected 104 hits this season and has an OBP of .356. He’s slugging .431 on the year.
  • Trout enters this game on a two-game hitting streak. During his last five outings he is hitting .294 with a double, four home runs, two walks and five RBIs.

Angels pitching rankings

  • The Angels average the 23rd-most strikeouts per nine innings (8.1) in the majors this season.
  • Los Angeles pitchers have a combined ERA of 4.87 ERA this year, which ranks 28th in MLB.
  • The Angels have a combined WHIP of 1.434 as a pitching staff, which is third-worst in baseball this season.
  • With 215 homers allowed, the Angels rank 27th in the league at preventing long balls.
  • Los Angeles pitchers struck out 13 Astros batters while allowing six hits in a 4-3 win last time out.
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Betting Guide

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