Astros vs. Angels Betting Lines, Odds, & Player Matchups September 27, 2025

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Data Skrive

Christian Walker takes a two-game home run streak into the Houston Astros’ (85-75) matchup with the Los Angeles Angels (72-88) and Mike Trout, who has also hit home runs in two consecutive games. The Astros are favored on the moneyline (-161) for this matchup with the Angels (+135), which starts at 9:38 p.m. ET on Saturday at Angel Stadium. Houston has A.J. Blubaugh starting things off, and Los Angeles counters with Caden Dana.

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Betting Odds

Astros to win vs Angels -161

Bet $20, Payout $32.42

Astros vs. Angels betting lines

  • Favorite: Astros (-161)
  • Underdog: Angels (+135)
  • Over/under: 9

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have compiled a 53-50 record in games they were listed as the moneyline favorite (winning 51.5% of those games).
  • Houston has gone 15-14 when playing as moneyline favorites with odds of -161 or shorter (51.7% winning percentage).
  • The Astros have an implied moneyline win probability of 61.7% in this contest.
  • In the 160 games in which bookmakers have set an over/under for Houston, it has combined with opponents to go over the total 72 times (72-81-7).
  • The Astros have covered 49.4% of their games this season, going 79-81-0 ATS.

Astros hitting info

  • Jose Altuve has hit a team-high 26 homers.
  • Altuve ranks 42nd in homers and 59th in RBI among all hitters in MLB.
  • Jeremy Pena is batting .304 to pace his team.
  • Pena currently ranks 111th in homers and 117th in RBI in the bigs.
  • Yainer Diaz is hitting .255 with 25 doubles, a triple, 19 home runs and 20 walks.
  • Carlos Correa is batting .276 with 29 doubles, 13 home runs and 45 walks.
  • Correa has hit safely in three straight games. During his last five outings he is batting .294 with two doubles, four walks and two RBIs.

Astros pitching rankings

  • The Astros pitching staff is No. 1 in MLB with a collective 9.4 strikeouts per nine innings.
  • Houston has the 14th-ranked team ERA across all MLB pitching staffs (3.91).
  • The Astros have the ninth-lowest WHIP in baseball (1.230).
  • The Astros allow the 21st-fewest home runs in baseball (198 total, 1.2 per game).
  • Houston its 4-3 loss the last time out, the team struck out four Angels batters while allowing eight hits.

Angels betting info, hitting leaders, & pitching

Angels betting info

  • The Angels have won 53, or 43.8%, of the 121 games they’ve played as underdogs this season.
  • Los Angeles is 26-33 this season when entering a game as the underdog by +135 or more on the moneyline.
  • The bookmakers’ moneyline implies a 42.6% chance of a victory for the Angels.
  • Los Angeles’ games have gone over the total in 85 of its 160 chances.
  • In 160 games with a spread this season, the Angels are 84-76-0 ATS.

Angels hitting info

  • Taylor Ward is batting .227 for Los Angeles with a team-high 103 RBI.
  • Among all hitters in the big leagues, Ward ranks 10th in home runs and 11th in RBI.
  • Nolan Schanuel’s batting average of .264 leads all Los Angeles hitters this season.
  • Schanuel is 174th in home runs and 151st in RBI among all hitters in the big leagues.
  • Jo Adell’s 37 home runs lead all Los Angeles hitters, and he’s slugging .486.
  • Trout has 104 hits and an OBP of .356 to go with a slugging percentage of .431 this season.
  • Trout heads into this game on a two-game hitting streak. In his last five games he is hitting .294 with a double, four home runs, two walks and five RBIs.

Angels pitching rankings

  • The Angels have an 8.1 K/9 this season as a pitching staff, which ranks 22nd in the majors.
  • Los Angeles has the 28th-ranked ERA (4.87) in the majors this season.
  • The Angels have a combined 1.434 WHIP as a pitching staff, third-highest in MLB.
  • The Angels have given up the third-most long balls so far this season with 215 home runs allowed.
  • Last time out, Los Angeles defeated the Astros, 4-3, with 13 strikeouts and six hits allowed.
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