Astros vs. Angels Betting Lines, Odds, & Player Matchups September 26, 2025

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Data Skrive

Taylor Ward takes a two-game home run streak into the Los Angeles Angels’ (71-87) matchup with the Houston Astros (85-74). The Astros are the moneyline favorite (-154) over the Angels (+130), and it begins at 9:38 p.m. ET on Friday at Angel Stadium. Houston has Jason Alexander set to start, while Los Angeles will counter with Kyle Hendricks.

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Betting Odds

Astros to win vs Angels -154

Bet $20, Payout $32.99

Astros vs. Angels betting lines

  • Favorite: Astros (-154)
  • Underdog: Angels (+130)
  • Over/under: 9

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have gone 53-49 in games they were favored on the moneyline (winning 52% of those games).
  • When it has played as moneyline favorites with odds of -154 or shorter, Houston has a record of 18-15 (54.5%).
  • The implied moneyline probablility in this matchup gives the Astros a 60.6% chance to win.
  • In the 159 games in which bookmakers have set an over/under for Houston, it has combined with opponents to go over the total 72 times (72-80-7).
  • The Astros have a 79-80-0 record against the spread this season (covering 49.7% of the time).

Astros hitting info

  • Jose Altuve has hit a team-best 26 homers.
  • Altuve ranks 40th in homers and 59th in RBI among all hitters in baseball.
  • Altuve has hit safely in two straight games. During his last five outings he is batting .412 with two doubles, three walks and three RBIs.
  • Jeremy Pena is batting .304 to lead his team.
  • Pena ranks 111th in homers and 109th in RBI among batters in MLB action.
  • Yainer Diaz is batting .253 with 23 doubles, a triple, 19 home runs and 20 walks.
  • Carlos Correa has 29 doubles, 13 home runs and 45 walks while hitting .274.
  • Correa has safely hit in two straight games. In his last five games he is hitting .222 with two doubles, four walks and two RBIs.

Astros pitching rankings

  • The pitching staff for the Astros has a collective 9.4 K/9 to lead the majors.
  • Houston has the 14th-ranked team ERA among all MLB pitching staffs (3.90).
  • Astros pitchers combine for the No. 8 WHIP in baseball (1.229).
  • The Astros allow the 21st-fewest home runs in baseball (196 total, 1.2 per game).
  • In its 11-5 win last time out, Houston struck out 12 Athletics batters while allowing 12 hits.

Angels betting info, hitting leaders, & pitching

Angels betting info

  • The Angels have been underdogs in 119 games this season and won 52 (43.7%) of those contests.
  • This season, Los Angeles has won 28 of its 63 games, or 44.4%, when it’s the underdog by at least +130 on the moneyline.
  • The bookmakers’ moneyline implies a 43.5% chance of a victory for the Angels.
  • Los Angeles and its opponents have gone over the total this season in 84 of its 158 opportunities.
  • The Angels have an ATS record of 83-75-0 in 158 games with a spread this season.

Angels hitting info

  • Ward is batting .228 this season with a team-high 36 home runs and 103 RBI.
  • In all of MLB, Ward ranks ninth in home runs and 11th in RBI.
  • Ward heads into this game on a seven-game hitting streak. In his last 10 games he is hitting .282 with six home runs and six RBIs.
  • Jo Adell is slugging .484 this season, with a team-best 36 homers while driving in 96 runs.
  • Adell ranks ninth in home runs and 18th in RBI among all batters in MLB.
  • Nolan Schanuel is batting .267 to lead Los Angeles, while adding 11 homers and 52 runs batted in this season.
  • Mike Trout has 101 hits and an OBP of .356 to go with a slugging percentage of .412 this season.

Angels pitching rankings

  • The Angels have an 8.0 K/9 this season as a pitching staff, which ranks 23rd in the majors.
  • Los Angeles has the 28th-ranked ERA (4.87) in the majors this season.
  • The Angels have a combined WHIP of 1.437 as a pitching staff, which is third-worst in baseball this season.
  • The Angels have allowed the third-most home runs this season with 213, or 1.3 per game.
  • Los Angeles earned a 3-2 win in its most recent game, striking out nine Royals batters while allowing two hits.
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Betting Guide

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