Astros vs. Athletics Betting Lines, Odds, & Player Matchups September 24, 2025

Data Skrive
Data Skrive

The Houston Astros (84-73) visit the Athletics (74-83) at 10:05 p.m. ET on Wednesday in a matchup of two of MLB’s most consistent batters. Jeremy Pena has a batting average of .304 (fifth in MLB) for the favored Astros (-146), while Jacob Wilson is second in MLB play hitting .318 this season for the underdog Athletics (+121). Hunter Brown starts for Houston while Sacramento will counter with Luis Severino.

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Moneyline

Astros to win vs Athletics -146

Bet $20, Payout $33.70

Astros vs. Athletics betting lines

  • Favorite: Astros (-146)
  • Underdog: Athletics (+121)
  • Over/under: 9

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have been favored on the moneyline 100 total times this season. They’ve gone 52-48 in those games.
  • When playing as a moneyline favorite with odds of -146 or shorter, the Astros have gone 21-16 (56.8%).
  • The implied moneyline probablility in this matchup gives the Astros a 59.3% chance to win.
  • The Astros have played in 157 games with a set over/under, and have combined with their opponents to go over the total 71 times (71-79-7).
  • The Astros have a 78-79-0 record against the spread this season (covering 49.7% of the time).

Astros hitting info

  • Jose Altuve has hit a team-best 26 homers.
  • Altuve ranks 39th in homers and 64th in RBI among all hitters in MLB play.
  • Pena is batting .304 to lead his team.
  • Pena ranks 110th in home runs and 107th in RBI this season.
  • Yainer Diaz has 23 doubles, a triple, 19 home runs and 20 walks while batting .256.
  • Carlos Correa has 27 doubles, 13 home runs and 43 walks while hitting .272.

Astros pitching rankings

  • The 9.4 strikeouts per nine innings compiled by the Astros pitching staff ranks first in the majors.
  • The Astros have a 3.88 team ERA that ranks 10th across all league pitching staffs.
  • The Astros have the sixth-lowest WHIP in the majors (1.226).
  • The Astros allow the 22nd-fewest home runs in baseball (192 total, 1.2 per game).
  • They lost to the Athletics 5-1 in their last game with seven strikeouts while allowing nine hits.

Athletics betting info, hitting leaders, & pitching

Athletics betting info

  • This season, the Athletics have won 55 out of the 117 games, or 47%, in which they’ve been the underdog.
  • The Athletics have a record of 24-41, a 36.9% win rate, when they’re set as the underdog by +121 or more by oddsmakers this season.
  • The oddsmakers’ moneyline implies a 45.2% chance of a victory for the Athletics.
  • The Athletics and their opponents have hit the over in 74 of their 157 games with a total this season.
  • In 157 games with a spread this season, the Athletics are 83-74-0 ATS.

Athletics hitting info

  • Brent Rooker is batting .264 with 30 home runs and 87 RBI for Sacramento this season.
  • Rooker is 21st in homers and 31st in RBI among all hitters in the big leagues.
  • Tyler Soderstrom leads Sacramento in runs batted in with 91 while batting .278 with 24 homers.
  • Soderstrom currently ranks 51st in home runs and 24th in RBI in the major leagues.
  • Soderstrom heads into this game on a two-game hitting streak. In his last five games he is batting .313 with a double, a walk and two RBIs.
  • Wilson leads Sacramento with a .318 batting average while slugging 13 homers and driving in 60 runs.
  • Nick Kurtz’s 33 home runs are most among Sacramento batters. He’s driven in 81 runs this season while slugging .612.
  • Kurtz enters this game on a two-game hitting streak. During his last five outings he is hitting .235 with two doubles, a home run, a walk and an RBI.

Athletics pitching rankings

  • The Athletics average the 20th-most strikeouts per nine innings (8.3) in the majors this season.
  • Athletics pitchers have a combined ERA of 4.70 ERA this year, which ranks 27th in MLB.
  • The Athletics have a combined WHIP of 1.362 as a pitching staff, which ranks 25th in MLB.
  • The Athletics have allowed the second-most home runs this season with 217, or 1.4 per game.
  • Last time out, they defeated the Astros, 5-1, with six strikeouts and three hits allowed.
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Betting Guide

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How to Bet Odds

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