In a Week 5 college football slate that has plenty of exciting matchups, the San Diego State Aztecs versus the Northern Illinois Huskies is a game to catch.
To pick up an edge prior to Week 5 in college football, read our odds breakdown below.
Below you’ll find our betting primers for this season, and uncover all of our expert picks here, too!
Week 5’s Closest Projected College Football Games (by Spread)
San Diego State (3-1) at Northern Illinois (1-3)
- Game Time: 3:30 p.m. ET | Saturday, September 27, 2025
- NIU Last Game: 6-3 L vs San Diego State
- SDSU Last Game: 6-3 W vs Northern Illinois
San Diego State -1.5 vs. Northern Illinois
Arkansas State (1-4) at Louisiana-Monroe (3-1)
- Game Time: 3 p.m. ET | Saturday, September 27, 2025
- ULM Last Game: 28-16 W vs Arkansas State
- Arkansas St Last Game: 28-16 L vs Louisiana-Monroe
Louisiana-Monroe -1.5 vs. Arkansas State
Marshall (2-2) at Louisiana (1-3)
- Game Time: 8 p.m. ET | Saturday, September 27, 2025
- Louisiana Last Game: 34-31 L vs Eastern Michigan
- Marshall Last Game: 42-28 W vs Middle Tennessee
Marshall -2.5 vs. Louisiana
No. 17 Alabama (2-1) at No. 5 Georgia (3-0)
- Game Time: 7:30 p.m. ET | Saturday, September 27, 2025
- UGA Last Game: 44-41 W vs Tennessee
- Alabama Last Game: 38-14 W vs Wisconsin
Georgia -2.5 vs. Alabama
No. 4 LSU (4-1) at No. 13 Ole Miss (5-0)
- Game Time: 3:30 p.m. ET | Saturday, September 27, 2025
- Ole Miss Last Game: 24-19 W vs LSU
- LSU Last Game: 24-19 L vs Ole Miss
Ole Miss -2.5 vs. LSU
TCU (3-1) at Arizona State (4-1)
- Game Time: 9 p.m. ET | Friday, September 26, 2025
- ASU Last Game: 27-24 W vs TCU
- TCU Last Game: 27-24 L vs Arizona State
Arizona State -3 vs. TCU
UConn (3-2) at Buffalo (2-3)
- Game Time: 3:30 p.m. ET | Saturday, September 27, 2025
- Buffalo Last Game: 20-17 L vs UConn
- UConn Last Game: 20-17 W vs Buffalo
UConn -3 vs. Buffalo
Eastern Michigan (1-4) at Central Michigan (3-2)
- Game Time: 1 p.m. ET | Saturday, September 27, 2025
- CMU Last Game: 24-13 W vs Eastern Michigan
- EMU Last Game: 24-13 L vs Central Michigan
Central Michigan -3 vs. Eastern Michigan
San Jose State (1-2) at Stanford (1-3)
- Game Time: 7:30 p.m. ET | Saturday, September 27, 2025
- Stanford Last Game: 48-20 L vs Virginia
- SJSU Last Game: 31-28 W vs Idaho
Stanford -3 vs. San Jose State
Louisiana Tech (3-1) at UTEP (1-3)
- Game Time: 9 p.m. ET | Saturday, September 27, 2025
- UTEP Last Game: 31-25 L vs Louisiana-Monroe
- La. Tech Last Game: 30-20 W vs Southern Miss
Louisiana Tech -3.5 vs. UTEP
BetDecider Team
The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.
