The Cleveland Guardians (49-50) host the Baltimore Orioles (44-55) on Wednesday at 6:40 p.m. ET. The Guardians are favored on the moneyline (-120) against the underdog Orioles (+101). Slade Cecconi starts for Cleveland while Baltimore will counter with Zach Eflin.

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Guardians vs. Orioles betting lines

• Favorite: Guardians (-120)
• Underdog: Orioles (+101)
• Over/under: 8.5

Guardians betting info, hitting leaders, & pitching

Guardians betting info

• The Guardians have a 23-15 record in games they were favored on the moneyline (winning 60.5% of those games).
• When it has played as moneyline favorites with odds of -120 or shorter, Cleveland has gone 18-11 (62.1%).
• The implied moneyline probablility in this matchup gives the Guardians a 54.5% chance to win.
• Cleveland has combined with opponents to go over the total 42 times this season for a 42-51-4 record against the over/under.
• The Guardians have gone 49-48-0 ATS this season.

Guardians hitting info

• Jose Ramirez has put up a team-high batting average of .294, while pacing the Guardians in home runs (20) and runs batted in (55).
• Among hitters in baseball, Ramirez ranks 20th in home runs and 43rd in RBI.
• Steven Kwan is batting .288 with 20 doubles, a triple, six home runs and 36 walks.
• Kwan ranks 204th in home runs and 172nd in RBI this year.
• Carlos Santana has seven doubles, 11 home runs and 45 walks while batting .231.
• Santana has safely hit in two games in a row. In his last five games he is batting .167 with two walks and two RBIs.
• Kyle Manzardo has 12 doubles, two triples, 16 home runs and 29 walks while batting .219.

Guardians pitching rankings

• The Guardians pitching staff ranks 12th in MLB with a collective 8.6 strikeouts per nine innings.
• Cleveland has the 16th-ranked team ERA across all MLB pitching staffs (3.95).
• The Guardians have the 24th-ranked WHIP in baseball (1.330).
• Guardians pitchers combine to surrender the 10th-fewest home runs in baseball (106 total, 1.1 per game).
• Cleveland defeated the Orioles 10-5 in its last game with seven strikeouts while allowing six hits.

Orioles betting info, hitting leaders, & pitching

Orioles betting info

• The Orioles have entered the game as underdogs 48 times this season and won 21, or 43.8%, of those games.
• This season, Baltimore has won 17 of its 39 games, or 43.6%, when it’s the underdog by at least +101 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Orioles have a 49.8% chance to win.
• So far this season, Baltimore and its opponents have hit the over in 42 of its 99 games with a total.
• In 99 games with a spread this season, the Orioles are 41-58-0 ATS.

Orioles hitting info

• Gunnar Henderson leads Baltimore with a .279 batting average. He’s also hit 11 homers and has 35 RBI.
• Among all hitters in MLB, Henderson ranks 111th in home runs and 148th in RBI.
• Ryan O’Hearn has collected 80 hits this season and has an OBP of .373. He’s slugging .451 on the year.
• O’Hearn ranks 95th among batters in the majors in home runs, and 139th in RBI.
• Jackson Holliday leads Baltimore in home runs with 13. He’s driven in 39 runs and is slugging .416.
• Holliday brings a three-game hitting streak into this game. In his last five games he is batting .286 with a home run, a walk and an RBI.
• Cedric Mullins leads Baltimore in home runs (13) and runs batted in (42) this season while batting .216.

Orioles pitching rankings

• The Orioles strike out 8.4 batters per nine innings as a pitching staff, 15th in MLB.
• Baltimore has the 27th-ranked ERA (5.01) in the majors this season.
• The Orioles have a combined WHIP of 1.427 as a pitching staff, which is fourth-worst in baseball this season.
• With 140 homers allowed, the Orioles rank 29th in the league at preventing long balls.
• Baltimore pitchers struck out seven Guardians hitters while allowing 14 base hits in a 10-5 loss its last time out.