Week 11 NFL action pits Christian McCaffrey and his San Francisco 49ers teammates up against the Arizona Cardinals at 4:05 p.m. ET on Sunday Below, we dig into McCaffrey’s stats and trends as they relate to his prop bets to help you pick out the top bets for the player and this contest.
Rushing Yards Prop
Bet $20, Payout $38.02
Christian McCaffrey to go over 72.5 yards
Christian McCaffrey Prop Lines
- Matchup: San Francisco 49ers at Arizona Cardinals
- Time: 4:05 p.m. ET
- Date: November 16, 2025
- Rushing yards prop: Over 72.5 (-111)
- Receiving yards prop: Over 50.5 (-110)
Christian McCaffrey Stats and Trends
- McCaffrey has carried the rock 180 times for a team-best 626 yards (62.6 ypg). He has scored four TDs on the ground.
- McCaffrey is averaging 62.6 rushing yards in 2025, 9.9 fewer than Sunday’s over/under.
- This season McCaffrey has bettered this week’s over/under for rushing yards (72.5) two times.
- His average rushing yards prop bet (67.5) is just a bit higher than his average total (62.6) this year.
- McCaffrey has gone over his rushing yards prop bet three times (in 10 opportunities) this year.
- He has scored multiple rushing touchdowns once this year, and has scored in three games.
- McCaffrey is also the top receiver for the 49ers, adding 69 catches for 692 yards (69.2 ypg) and four receiving touchdowns.
Recent Performances vs. the Cardinals
| Week | Opponent | Rush Yards Allowed | Rush TDs Allowed |
|---|---|---|---|
| 1 | Saints | 107 | 1 |
| 2 | Panthers | 49 | 0 |
| 3 | 49ers | 73 | 0 |
| 4 | Seahawks | 155 | 1 |
| 5 | Titans | 78 | 1 |
| 6 | Colts | 150 | 2 |
| 7 | Packers | 94 | 2 |
| 9 | Cowboys | 123 | 0 |
| 10 | Seahawks | 198 | 2 |
49ers Away Splits
- On the road, the 49ers average more points (22.8 per game) than they do overall (22.0). They also allow fewer points on the road (22.8) than they do overall (23.0).
- The 49ers accumulate 350.2 yards per game in road games (6.0 fewer than overall), and give up 352.7 in away games (13.3 more than overall).
- The 49ers accumulate 259.5 passing yards per game in away games (1.9 fewer than overall) and give up 242.5 on the road (13.7 more than overall).
- On the road, the 49ers pick up fewer rushing yards (90.7 per game) than they do overall (94.8). But they also allow fewer rushing yards away from home (110.2) than overall (110.6).
- The 49ers convert fewer third downs in road games (45.8%) than they do overall (46.5%) and allow opponents to convert on more third downs away from home (41.8%) than overall (40.5%).
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