Orioles vs. Cardinals Betting Lines, Odds, & Player Matchups May 28, 2025

Data Skrive
Data Skrive

The Baltimore Orioles (19-34) host the St. Louis Cardinals (30-24) on Wednesday at Oriole Park at Camden Yards, beginning at 6:35 p.m. ET. The Orioles are favored on the moneyline (-123), while the Cardinals are +103 underdogs. The Cardinals are favored against the spread (1.5) with +158 odds, despite being the moneyline underdog. Baltimore’s Cade Povich starts against St. Louis’ Miles Mikolas.

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Money Line

Orioles to win vs Cardinals -123

Bet $20, Payout $36.26

Orioles vs. Cardinals betting lines

  • Favorite: Orioles (-123)
  • Underdog: Cardinals (+103)
  • Over/under: 8.5

Orioles betting info, hitting leaders, & pitching

Orioles betting info

  • The Orioles have been favored on the moneyline 28 total times this season. They’ve finished 9-19 in those games.
  • When it has played as moneyline favorites with odds of -123 or shorter, Baltimore has a record of 8-15 (34.8%).
  • The implied moneyline probablility in this matchup gives the Orioles a 55.2% chance to win.
  • Baltimore has played in 53 games with set over/under, and have combined with opponents to go over the total 25 times (25-25-3).
  • The Orioles have an 18-35-0 record ATS this season (covering only 34% of the time).

Orioles hitting info

  • Ryan O’Hearn leads the Orioles with a team-best batting average of .340.
  • Among all hitters in baseball, O’Hearn’s home run total ranks 54th and his RBI tally ranks 149th.
  • O’Hearn enters this game on a six-game hitting streak. In his last 10 games he is batting .447 with three doubles, a home run, five walks and four RBIs.
  • Cedric Mullins has hit 10 home runs with 31 runs batted in. Both pace his team.
  • Mullins ranks 25th in homers and 27th in RBI among MLB batters this season.
  • Gunnar Henderson has 10 doubles, two triples, seven home runs and 17 walks while batting .266.
  • Henderson brings a two-game hitting streak into this matchup. In his last five games he is batting .353 with two doubles, five walks and two RBIs.
  • Adley Rutschman is batting .211 with seven doubles, a triple, five home runs and 24 walks.

Orioles pitching rankings

  • The Orioles pitching staff ranks 24th in the majors with a collective 7.8 strikeouts per nine innings.
  • Baltimore has a 5.45 team ERA that ranks 29th across all MLB pitching staffs.
  • The Orioles average MLB’s fourth-worst WHIP (1.467).
  • The Orioles give up the most home runs in baseball (84 total, 1.6 per game).
  • In its 5-2 win last time out, Baltimore struck out 10 Cardinals batters while allowing four hits.

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • The Cardinals have been underdogs in 34 games this season and won 19 (55.9%) of those contests.
  • St. Louis has entered 21 games this season as the underdog by +103 or more and is 9-12 in those contests.
  • The moneyline for this contest implies a 49.3% chance of a victory for the Cardinals.
  • St. Louis’ games have gone over the total in 27 of its 54 chances.
  • The Cardinals are 31-23-0 ATS in their 54 games with a spread this season.

Cardinals hitting info

  • Brendan Donovan leads St. Louis with a batting average of .328. He’s also hit three home runs with 22 RBI.
  • Donovan ranks 192nd in homers and 107th in RBI among all batters in MLB.
  • Donovan brings a three-game hitting streak into this matchup. During his last five outings he is batting .313 with two doubles and three walks.
  • Lars Nootbaar is slugging .390 this season, with a team-best seven homers while driving in 25 runs.
  • Nootbaar ranks 74th among hitters in the majors in home runs, and 77th in RBI.
  • Nolan Arenado has 44 hits this season and a slash line of .234/.306/.378.
  • Victor Scott II is batting .273 with an OBP of .346 and a slugging percentage of .373 this season.

Cardinals pitching rankings

  • The Cardinals average just 7.8 strikeouts per nine innings as a pitching staff, which ranks 29th in the majors.
  • St. Louis has pitched to a 3.73 ERA this season, which ranks 12th in baseball.
  • Cardinals pitchers have a 1.221 WHIP this season, 12th in the majors.
  • The Cardinals have given up the third-fewest long balls so far this season with only 41 home runs allowed.
  • St. Louis suffered a 5-2 defeat in its most recent game, as its pitchers struck out eight Orioles batters while allowing 10 hits.
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Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …