The Arizona Wildcats (5-3) and the Kansas Jayhawks (5-4) square off on Saturday, November 8, 2025 at Arizona Stadium in a clash of Big 12 opponents.

The Wildcats are the favorites (-5.5) in their game versus the Jayhawks, with the over/under at 56.5 points. (In terms of the moneyline, the Wildcats are -199 and the Jayhawks are +165.)

Keep reading to check out our betting preview for this this contest between the Wildcats and the Jayhawks, and discover all of our expert predictions here, too!

Arizona vs. Kansas betting lines

• Spread favorite: Wildcats (-5.5)
• Moneyline: Wildcats (-199), Jayhawks (+165)
• Total: 56.5 points
• TV Channel: ESPN2
• Live Stream: Fubo

Arizona vs. Kansas betting info and stats

Arizona has four wins against the spread so far this season (4-3-0). Arizona is undefeated ATS (2-0) when favorites by at least 5.5 points. Arizona is 3-1 in the four games this season it has been the moneyline favorite. Kansas is 3-6-0 against the spread so far this season. When Kansas is an underdog of 5.5 points or more, it has have yet to cover the spread. This will be the third game this year Kansas is an underdog on the moneyline, after losing the previous two such games.

Arizona vs. Kansas recent stats and trends

Arizona Wildcats

• Arizona is 1-2 against the spread and 1-2 overall in its past three matchups.
• In all of those games, the final combined score has gone over the set total.
• The past three Arizona games averaged 7.5 fewer points (49.0) than this matchup’s over/under.

Kansas Jayhawks

• Kansas has not covered a spread (0-3) while going 1-2 overall over its last three matchups.
• The final combined score of the last three Kansas games has gone over the set total every time.
• The last three Kansas games averaged 56.3 total points, 0.2 fewer points than this matchup’s over/under.

Arizona vs. Kansas key players

Arizona Wildcats

• Noah Fifita has thrown for 2,042 yards (255.3 ypg) to lead Arizona, completing 65.4% of his passes and collecting 21 touchdown passes compared to four interceptions this season. He’s also contributed in the ground game with 84 rushing yards on 62 carries with three rushing touchdowns.
• Ismail Mahdi has racked up 530 yards on 80 carries while finding paydirt two times.
• Quincy Craig has collected 234 yards on 37 attempts, scoring one time.
• Jayin Whatley has hauled in 33 receptions for 404 yards (50.5 yards per game) to lead the team so far this season. He’s found the end zone four times as a receiver.
• Kris Hutson has caught 29 passes for 355 yards (59.2 yards per game) and three touchdowns this year.
• Tre Spivey has been the target of 18 passes and hauled in 11 grabs for 280 yards, an average of 35.0 yards per contest. He’s found the end zone six times through the air this season.
• Riley Wilson paces the team with 3.0 sacks, and also has 3.0 TFL and 19 tackles.
• Dalton Johnson, Arizona’s tackle leader, has 47 tackles, 1.0 TFL, one sack, and two interceptions this year.
• Jay’Vion Cole has a team-high three interceptions to go along with 19 tackles, 3.0 TFL, one sack, and four passes defended.

Kansas Jayhawks

• Jalon Daniels has racked up 1,991 yards on 66.7% passing while collecting 20 touchdown passes with three interceptions this season. He’s also rushed for 263 yards with two scores.
• Leshon Williams is his team’s leading rusher with 71 carries for 396 yards, or 49.5 per game. He’s found the end zone six times on the ground, as well.
• Daniel Hishaw Jr. has run for 363 yards across 76 attempts, scoring four touchdowns.
• Emmanuel Henderson Jr.’s 573 receiving yards (63.7 yards per game) are a team high. He has 36 catches on 61 targets with four touchdowns.
• Cam Pickett has put up a 361-yard season so far with three touchdowns. He’s caught 33 passes on 41 targets.
• Boden Groen’s 29 grabs (on 36 targets) have netted him 332 yards (36.9 ypg) and four touchdowns.
• Leroy Harris III has 4.5 sacks to lead the team, and also has 5.0 TFL and 18 tackles.
• Trey Lathan has 59 tackles, 4.0 TFL, 1.5 sacks, and one interception, and leads the team in both tackles and interceptions.