Diamondbacks vs. Giants Betting Lines, Odds, & Player Matchups September 17, 2025

Data Skrive
Data Skrive

James McCann rides a two-game home run streak into the Arizona Diamondbacks’ (76-75) matchup against the San Francisco Giants (75-75). The Diamondbacks are favored on the moneyline (-129) in this contest with the Giants (+109), which starts at 3:40 p.m. ET on Wednesday at Chase Field. Arizona’s Brandon Pfaadt gets the start against San Francisco’s Justin Verlander.

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Money Line

Diamondbacks to win vs Giants -129

Bet $20, Payout $35.50

Diamondbacks vs. Giants betting lines

  • Favorite: Diamondbacks (-129)
  • Underdog: Giants (+109)
  • Over/under: 9

Diamondbacks betting info, hitting leaders, & pitching

Diamondbacks betting info

  • The Diamondbacks have been favored on the moneyline 85 total times this season. They’ve gone 44-41 in those games.
  • Arizona has gone 27-25 when playing as moneyline favorites with odds of -129 or shorter (51.9% winning percentage).
  • The Diamondbacks have an implied moneyline win probability of 56.3% in this matchup.
  • In the 150 games in which bookmakers have set an over/under for Arizona, it has combined with opponents to go over the total 72 times (72-69-9).
  • The Diamondbacks have a 78-72-0 record ATS this season.

Diamondbacks hitting info

  • Geraldo Perdomo leads the Diamondbacks with 97 runs batted in while accumulating a team-high batting average of .290.
  • Perdomo ranks 81st in home runs and 13th in RBI among all hitters in baseball.
  • Perdomo has hit safely in six games in a row. During his last 10 games he is hitting .400 with a double, a triple, three home runs, eight walks and nine RBIs.
  • Corbin Carroll has hit 30 home runs to lead his team.
  • Carroll ranks 16th in home runs and 52nd in RBI among MLB hitters this season.
  • Carroll brings a two-game hitting streak into this game. During his last five outings he is batting .235 with a double, seven walks and two RBIs.
  • Ketel Marte has 23 doubles, 25 home runs and 63 walks while hitting .277.
  • Gabriel Moreno is hitting .289 with 11 doubles, a triple, nine home runs and 21 walks.

Diamondbacks pitching rankings

  • The pitching staff for the Diamondbacks has a collective 8.0 K/9, which ranks 22nd in MLB.
  • Arizona has the 22nd-ranked team ERA across all MLB pitching staffs (4.45).
  • The Diamondbacks average baseball’s 21st-ranked WHIP (1.318).
  • Diamondbacks pitchers combine to allow the 17th-fewest home runs in baseball (180 total, 1.2 per game).
  • In its 8-1 win last time out, Arizona struck out 10 Giants batters while allowing two hits.

Giants betting info, hitting leaders, & pitching

Giants betting info

  • The Giants have been underdogs in 62 games this season and won 29 (46.8%) of those contests.
  • San Francisco has a record of 19-23, a 45.2% win rate, when it’s set as an underdog of +109 or more by sportsbooks this season.
  • The implied probability of a win by the Giants, based on the moneyline, is 47.8%.
  • So far this season, San Francisco and its opponents have hit the over in 70 of its 150 games with a total.
  • The Giants are 69-81-0 against the spread this season.

Giants hitting info

  • Rafael Devers leads San Francisco in home runs with 31 and runs batted in with 102.
  • Among all batters in the majors, Devers is 12th in homers and ninth in RBI.
  • Jung Hoo Lee leads San Francisco in batting with a .264 average while slugging eight homers and driving in 52 runs.
  • Among all major league hitters, Lee is 235th in homers and 144th in RBI.
  • Willy Adames has collected 126 base hits, an OBP of .318 and a slugging percentage of .427 this season.
  • Matt Chapman has collected 99 hits this season and has an OBP of .350. He’s slugging .449 on the year.

Giants pitching rankings

  • The Giants average the 12th-most strikeouts per nine innings (8.6) in the majors this season.
  • San Francisco has the 10th-best ERA (3.86) in the majors this season.
  • The Giants have a combined WHIP of 1.307 as a pitching staff, which ranks 18th in MLB.
  • The Giants have given up the fewest long balls so far this season with only 128 home runs allowed.
  • San Francisco pitchers struck out six Diamondbacks hitters while allowing nine base hits in an 8-1 loss its last time out.
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Betting Guide

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