Diamondbacks vs. Giants Betting Lines, Odds, & Player Matchups September 16, 2025

Data Skrive
Data Skrive

Booksmakers give the Arizona Diamondbacks (76-75) the edge (-125 on the moneyline) to prolong their three-game winning streak when they play the San Francisco Giants (75-75), at +105, on Tuesday at 9:40 p.m. ET. San Francisco has not named a starting pitcher while Arizona is expected to start Eduardo Rodriguez.

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Moneyline

Diamondbacks to win vs Giants -125

Bet $20, Payout $36.00

Diamondbacks vs. Giants betting lines

  • Favorite: Diamondbacks (-125)
  • Underdog: Giants (+105)
  • Over/under: 9

Diamondbacks betting info, hitting leaders, & pitching

Diamondbacks betting info

  • The Diamondbacks have put together a 44-41 record in games they were listed as the moneyline favorite (winning 51.8% of those games).
  • When playing as moneyline favorites with odds of -125 or shorter, Arizona has a 27-29 record (winning 48.2% of its games).
  • Based on this game’s moneyline, the Diamondbacks have an implied win probability of 55.6%.
  • Arizona has played in 150 games with over/under set, and have combined with opponents to go over the total 72 times (72-69-9).
  • The Diamondbacks have gone 78-72-0 ATS this season.

Diamondbacks hitting info

  • Geraldo Perdomo leads the Diamondbacks in runs batted in (97) and has a team-best batting average of .290.
  • Among all hitters in MLB play, Perdomo’s home run total ranks 80th and his RBI tally ranks 12th.
  • Perdomo enters this game on a six-game hitting streak. In his last 10 outings he is hitting .400 with a double, a triple, three home runs, eight walks and nine RBIs.
  • Corbin Carroll’s 30 home runs are a team-high mark.
  • Carroll ranks 15th in home runs and 50th in RBI among hitters in MLB action.
  • Carroll enters this game on a two-game hitting streak. During his last five outings he is hitting .235 with a double, seven walks and two RBIs.
  • Ketel Marte is batting .277 with 23 doubles, 25 home runs and 63 walks.
  • Gabriel Moreno is batting .289 with 11 doubles, a triple, nine home runs and 21 walks.

Diamondbacks pitching rankings

  • The pitching staff for the Diamondbacks has a collective eight K/9, which ranks 22nd in the majors.
  • Arizona’s 4.45 team ERA ranks 22nd across all MLB pitching staffs.
  • Pitchers for the Diamondbacks combine for the 20th-ranked WHIP in the majors (1.318).
  • The Diamondbacks allow the 18th-fewest home runs in baseball (180 total, 1.2 per game).
  • Arizona defeated the Giants 8-1 in its last game with 10 strikeouts while allowing two hits.

Giants betting info, hitting leaders, & pitching

Giants betting info

  • The Giants have won 29, or 46.8%, of the 62 games they’ve played as underdogs this season.
  • San Francisco has a record of 20-24, a 45.5% win rate, when it’s set as an underdog of +105 or more by bookmakers this season.
  • The moneyline for this contest implies a 48.8% chance of a victory for the Giants.
  • Games involving San Francisco have gone over the total set by oddsmakers in 70 of 150 chances this season.
  • In 150 games with a spread this season, the Giants are 69-81-0 ATS.

Giants hitting info

  • Rafael Devers leads San Francisco in home runs with 31 and runs batted in with 102.
  • Among all hitters in MLB, Devers is 12th in homers and eighth in RBI.
  • Jung Hoo Lee leads San Francisco in batting with a .264 average while slugging eight homers and driving in 52 runs.
  • Lee is 234th in home runs and 143rd in RBI among all major league hitters this season.
  • Willy Adames has 126 hits this season and a slash line of .230/.318/.427.
  • Matt Chapman has 99 hits and an OBP of .350 to go with a slugging percentage of .449 this season.

Giants pitching rankings

  • The Giants have an 8.6 K/9 this season as a pitching staff, which ranks 13th in the majors.
  • San Francisco has the 10th-best ERA (3.86) in the majors this season.
  • Giants pitchers have a 1.307 WHIP this season, 18th in the majors.
  • With just 128 homers allowed, the Giants rank first in the league at preventing long balls.
  • San Francisco suffered an 8-1 defeat in its most recent game, as its pitchers struck out six Diamondbacks batters while allowing nine hits.
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