NFL play for Week 9 includes the Buffalo Bills and James Cook facing the Kansas City Chiefs at 4:25 p.m. ET on Sunday. Below, we take a look at Cook’s stats and trends as they relate to his prop bets to help you find the best bets for the player and this contest.

James Cook Prop Lines

• Matchup: Buffalo Bills vs. Kansas City Chiefs
• Time: 4:25 p.m. ET
• Date: November 2, 2025
• Rushing yards prop: Over 72.5 (-114)
• Receiving yards prop: Over 12.5 (-114)

James Cook Stats and Trends

• Cook leads the team with 753 yards (107.6 ypg) on 126 carries and has scored seven rushing scores.
• Cook’s rushing yards over/under for Sunday is 72.5. That is 35.1 fewer yards than his 107.6 season average.
• Cook has had more than 72.5 rushing yards in five games this season (71.4%).
• Sportsbooks have set his rushing yards prop at 69.6 on average. He has bettered it by picking up 107.6 rushing yards per game.
• In five of seven opportunities (71.4%), Cook has gone beyond his rushing yards prop bet.
• He has scored multiple rushing TDs twice this season, and has scored in five games overall.
• Cook also has 12 receptions for 89 yards.

Recent Performances vs. the Chiefs

Bills Home Splits

• The Bills score 30.8 points per game in home games (1.2 more than their overall average), and concede 25.8 at home (4.9 more than overall).
• The Bills rack up 394 yards per game at home (11.1 more than their overall average), and concede 336 at home (23.9 more than overall).
• In home games, the Bills accumulate 257 passing yards per game and give up 179. That’s more than they gain (218.4) and allow (161.9) overall.
• The Bills accumulate 137 rushing yards per game at home (27.4 less than their overall average), and give up 157 at home (6.7 more than overall).
• The Bills’ offensive third-down percentage (46.7%) and defensive third-down percentage (50%) in home games are both higher than their overall averages of 43.8% and 40.2%, respectively.