The Arizona Wildcats (4-2) and the Houston Cougars (5-1) play on Saturday, October 18, 2025 at TDECU Stadium in a battle of Big 12 opponents.

The Wildcats are favored, but by less than a field goal (-1.5), against the Cougars. The over/under for this game is 47.5 points.

Read on for our preview for this this matchup between the Wildcats and the Cougars, and discover all of our betting picks here, too!

Arizona vs. Houston betting lines

• Spread favorite: Wildcats (-1.5)
• Moneyline: Wildcats (-116), Cougars (-103)
• Total: 47.5 points
• TV Channel: FOX Sports 1
• Live Stream: Fubo

Arizona vs. Houston betting info and stats

Arizona has won three games against the spread this season (3-2-0). In two games played when favored by at least 1.5 points, Arizona is undefeated ATS at 2-0. Arizona has won both games as the moneyline favorite this season. Houston has four wins against the spread through six opportunities this season (4-2-0). When Houston is an underdog of 1.5 points or more, it has not yet covered the spread. This is the second time this year Houston is the moneyline underdog. The Cougars lost the first one.

Arizona vs. Houston recent stats and trends

Arizona Wildcats

• Arizona is 1-2 against the spread and 1-2 overall over its last three games.
• Arizona and its opponents have hit the over in two of those games.
• The past three Arizona games averaged 3.0 more points (50.5) than this matchup’s over/under.

Houston Cougars

• Houston has covered the spread once in its last three contests while putting up a 1-2 record straight-up in those games.
• The final combined score of the last three Houston games has surpassed the set total two times.
• Houston’s past three outings have ended with an average of 48.8 points scored. That’s 1.3 more points than this contest’s over/under.

Arizona vs. Houston key players

Arizona Wildcats

• Noah Fifita has thrown for 1,560 yards (260.0 ypg) to lead Arizona, completing 62.7% of his passes and collecting 15 touchdown passes compared to four interceptions this season.
• Ismail Mahdi has racked up 403 yards on 71 carries while finding the end zone one time as a runner.
• This season, Quincy Craig has carried the ball 28 times for 207 yards (41.4 per game) and one touchdown.
• Jayin Whatley has hauled in 25 catches for 328 yards (54.7 yards per game) to lead the team so far this season. He’s found the end zone three times as a receiver.
• Kris Hutson has put together a 262-yard season so far with two touchdowns, hauling in 20 passes on 32 targets.
• Chris Hunter has a total of 239 receiving yards so far this year, hauling in 17 throws and scoring two touchdowns.
• Riley Wilson has 3.0 sacks to pace the team, and also has 3.0 TFL and 12 tackles.
• Dalton Johnson, Arizona’s top tackler, has 28 tackles, 1.0 TFL, one sack, and one interception this year.
• Jay’Vion Cole leads the team with two interceptions, while also putting up 12 tackles, 2.0 TFL, one sack, and three passes defended.

Houston Cougars

• Conner Weigman has been a dual threat for Houston this season. He has 1,216 passing yards (202.7 per game) while completing 61.5% of his passes. He’s thrown eight touchdown passes and two interceptions this season. On the ground, he’s compiled 148 yards (24.7 ypg) on 51 carries with five rushing touchdowns.
• Dean Connors has rushed for 438 yards on 95 carries so far this year while scoring four times on the ground.
• Amare Thomas has hauled in 441 receiving yards on 23 receptions to pace his squad so far this season while scoring two touchdowns as a receiver.
• Tanner Koziol has recorded 310 receiving yards (51.7 yards per game) and two touchdowns on 30 receptions.
• Stephon Johnson Jr.’s 25 targets have resulted in 13 catches for 275 yards and two touchdowns.
• Corey Platt Jr. leads the team with 2.5 sacks, and also has 2.0 TFL and 15 tackles.
• Jalen Garner, Houston’s top tackler, has 27 tackles, 1.0 TFL, and two sacks this year.
• C.J. Douglas has picked off a team-high one pass. He also has three tackles and one pass defended to his name.