The No. 13 Ole Miss Rebels (4-0) and the No. 4 LSU Tigers (4-0) play on Saturday, September 27, 2025 at Vaught-Hemingway Stadium in a clash of SEC foes.
The Rebels are favored, but by less than a field goal (-2.5), versus the Tigers. The over/under for this game is 57.5 points.
Read on for our betting primer for this this game between the Rebels and the Tigers, and find all of our betting picks here, too!
Betting Odds
Bet $20, Payout $38.35
Ole Miss -2.5 vs. LSU
Ole Miss vs. LSU betting lines
- Spread favorite: Rebels (-2.5)
- Moneyline: Rebels (-131), Tigers (+110)
- Total: 57.5 points
- TV Channel: ABC (KBMY – Bismarck)
- Live Stream: Fubo
Ole Miss vs. LSU betting info and stats
- Ole Miss is 3-1-0 against the spread in four opportunities this season. Ole Miss has a 3-1 ATS record when favored by at least 2.5 points. Ole Miss has been moneyline favorites four times this season, winning each game. LSU, through four games with a set spread so far this season, has gone 2-2-0 against the spread. In the one game LSU has been an underdog by at least 2.5 points this season, it has covered the spread. LSU has been an underdog on the moneyline one time so far this season, and won that game.
Ole Miss vs. LSU recent stats and trends
Ole Miss Rebels
LSU Tigers
Ole Miss vs. LSU key players
Ole Miss Rebels
- Trinidad Chambliss has been a dual threat for Ole Miss so far this season. He has 719 passing yards, completing 67.7% of his passes and collecting four touchdown passes this season. He’s rushed for 195 yards (48.8 ypg) on 36 carries with two rushing touchdowns.
- Kewan Lacy has racked up 358 yards on 79 carries while finding paydirt seven times as a runner. He’s also caught eight passes for 47 yards (15.7 per game).
- Harrison Wallace III’s team-high 343 yards as a receiver have come on 16 receptions (out of 31 targets) with two touchdowns.
- Deuce Alexander has grabbed 14 passes while averaging 62.3 yards per game and scoring one touchdown.
- Dae’Quan Wright’s eight catches have yielded 213 yards and two touchdowns.
- Zxavian Harris leads the team with 2.0 sacks, and also has 4.0 TFL, 21 tackles, and one interception.
- Jaden Yates is the team’s tackle leader this year. He’s picked up 28 tackles.
- Cedrick Beavers has a team-leading one interception to go along with 1.0 TFL and one pass defended.
LSU Tigers
- Garrett Nussmeier leads LSU with 960 yards on 94-of-137 passing with six touchdowns compared to two interceptions this season.
- Caden Durham has run for 213 yards on 52 carries so far this year while scoring two times on the ground.
- Harlem Berry has run for 87 yards across 15 attempts.
- Aaron Anderson has racked up 293 receiving yards on 21 catches to pace his team so far this season.
- Barion Brown has caught 20 passes and compiled 199 receiving yards (49.8 per game) with one touchdown.
- Bauer Sharp’s 20 targets have resulted in 14 grabs for 170 yards and one touchdown.
- Damien Shanklin has racked up 2.0 sacks to lead the team, while also recording 2.0 TFL.
- West Weeks is the team’s top-tackler this year. He’s racked up 24 tackles, 1.0 TFL, and 0.5 sacks.
- Dashawn Spears has picked off a team-high two passes. He also has two passes defended to his name.
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BetDecider Team
The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.
