The Mississippi State Bulldogs (1-0) host the No. 12 Arizona State Sun Devils (1-0) at Davis Wade Stadium at Scott Field on Saturday, September 6, 2025.

The Bulldogs are underdogs, but by less than a touchdown (+6.5), versus the Sun Devils (with an over/under of 58.5 points).

Keep reading to check out our preview for this this matchup between the Sun Devils and the Bulldogs, and find all of our betting picks here, too!

Arizona State vs. Mississippi State betting lines

• Spread favorite: Sun Devils (-6.5)
• Moneyline: Sun Devils (-240), Bulldogs (+196)
• Total: 58.5 points
• TV Channel: ESPN2
• Live Stream: Fubo

Arizona State vs. Mississippi State betting info and stats

Arizona State has yet to win a game against the spread this season (0-1-0). Arizona State has yet to cover the spread when the favorite by at least 6.5 points (a 0-1 ATS record). In one game as the moneyline favorite, Arizona State won. Mississippi State, in one game with a spread so far this season, has not lost (1-0-0) against the spread. This is the first time on the year Mississippi State is an underdog on the moneyline.

Arizona State vs. Mississippi State key players

Arizona State Sun Devils

• Last year Sam Leavitt put up 2,885 passing yards — including a 61.7% completion percentage — with 24 touchdowns and six interceptions (221.9 yards per game). His rushing performance consisted of 110 carries for 443 yards and five TDs.
• Cameron Skattebo took 293 carries for 1,711 yards (131.6 per game) and scored 21 touchdowns last year. When it comes to receiving, he caught 45 passes for 605 yards (46.5 per game) and three TDs.
• Jordyn Tyson amassed 75 receptions for 1,101 yards and 10 touchdowns last year. He was targeted 113 times, and averaged 91.8 yards per game.
• Xavier Guillory reeled in 22 passes for 339 yards and five touchdowns, averaging 28.3 yards per game last year.
• Elijah O’Neal did his thing last season with an incredible stat line of four sacks, four TFL and 27 tackles.
• Myles Rowser was a wrecking ball on the field, collecting 93 tackles, three TFL, and one sack last year.
• Keith Abney collected three interceptions while adding 46 tackles and three passes defended last year.

Mississippi State Bulldogs

• Michael Van Buren Jr. connected on 54.7% of his passes to throw for 1,886 yards and 11 touchdowns last season.
• Davon Booth tallied 759 rushing yards and five touchdowns on the ground during last year’s campaign.
• Last season Johnnie Daniels rushed for 540 yards. He also scored four total touchdowns.
• Kevin Coleman Jr. averaged 77.7 receiving yards and racked up six receiving touchdowns over the course of the 2024 season.
• Jordan Mosley hauled in three touchdowns and had 405 receiving yards (33.8 ypg) in 2024.
• Kelly Akharaiyi played his way to two receiving touchdowns and 391 receiving yards (32.6 ypg) last season.
• Last year Zakari Tillman put pressure on opposing quarterbacks with 3.5 sacks, and added three TFL, 28 tackles, and one interception.
• Stone Blanton was a playmaker on defense last season with 115 tackles, two TFL, and 0.5 sacks.
• Last year Tillman intercepted one pass to go along with 28 tackles, three TFL, 3.5 sacks, and one pass defended.