The USC Trojans (0-0) take on the Missouri State Bears (0-0) at Los Angeles Memorial Coliseum on Saturday, August 30, 2025.

The Trojans are expected to come out on top by at least two touchdowns (currently -36.5) against the Bears. The over/under for this game is 59.5 points.

Below you can find our betting preview for this this contest between the Trojans and the Bears, and discover all of our betting picks here, too!

USC vs. Missouri State betting lines

• Spread favorite: Trojans (-36.5)
• Moneyline: Trojans (-16667), Bears (+2625)
• Total: 59.5 points
• TV Channel: Big Ten Network
• Live Stream: Fubo

USC vs. Missouri State betting info and stats

• USC covered the spread eight times in 13 games last year.
• Last season, six of USC’s 13 games went over the point total.
• Missouri State beat the spread five times in 11 games last year.
• There were seven Missouri State games (out of 11) that went over the total last year.

USC vs. Missouri State key players

USC Trojans

• Miller Moss put up a passing stat line last year of 2,555 yards with a 64.4% completion rate (233-for-362), 18 touchdowns, nine interceptions, and an average of 283.9 yards per game.
• Last year, Jo’Quavious Marks rushed for 1,133 yards on 198 carries (94.4 yards per game) and scored nine times. Marks also collected 47 catches for 321 yards.
• Quinten Joyner ran for 478 yards on 63 carries (39.8 yards per game), with three rushing touchdowns last year.
• In the previous season, Makai Lemon grabbed 52 passes (on 72 targets) for 764 yards (58.8 per game). He also found the end zone three times.
• Ja’Kobi Lane also impressed receiving last season. He had 43 receptions for 525 yards and 12 touchdowns. He was targeted 71 times.
• Zachariah Branch hauled in 47 passes on 79 targets for 503 yards and one touchdown, compiling 41.9 receiving yards per game.
• Easton Mascarenas-Arnold put together an impressive resume last season of three sacks, four TFL, 90 tackles, and two interceptions.
• Jaylin Smith collected two interceptions while adding 49 tackles, three TFL, and two passes defended last year.

Missouri State Bears

• Jacob Clark completed 69.1% of his passes to throw for 3,604 yards and 26 touchdowns last season.
• Jacardia Wright averaged 68.7 rushing yards per game and tallied 14 rushing touchdowns. Wright complemented his performance on the ground with 2.9 receptions per game to average 36.6 receiving yards.
• Jayden Becks ran for seven touchdowns on 460 yards a year ago. Becks also was efficient as a receiver, accumulating 20 receptions for 235 yards with two touchdowns.
• Hunter Wood was targeted 5.7 times per game and piled up 770 receiving yards and three touchdowns over the course of 2024.
• Lance Mason averaged 53.6 receiving yards on 3.4 targets per game in 2024, scoring six touchdowns.
• Jmariyae Robinson grabbed 38 passes on his way to 585 receiving yards and four touchdowns a season ago.
• Last year Darion Smith put pressure on opposing quarterbacks with seven sacks, and added three tackles.
• Todric McGee had a stellar defensive performance last season with 16 tackles, one TFL, and one interception.
• Lemondre Joe racked up three interceptions in addition to 10 tackles a year ago.