Orioles vs. Astros Betting Lines, Odds, & Player Matchups August 22, 2025

Data Skrive
Data Skrive

The Baltimore Orioles (59-68) host the Houston Astros (70-58) on Friday at Oriole Park at Camden Yards, beginning at 7:05 p.m. ET. The Orioles are favored on the moneyline (-112), while the Astros are -107 underdogs. The Astros are spread favorites (1.5) with +150 odds, despite being the moneyline underdog. Cade Povich starts for Baltimore while Houston will counter with Lance McCullers.

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Moneyline

Orioles to win vs Astros -112

Bet $20, Payout $37.86

Orioles vs. Astros betting lines

  • Favorite: Orioles (-112)
  • Underdog: Astros (-107)
  • Over/under: 9.5

Orioles betting info, hitting leaders, & pitching

Orioles betting info

  • The Orioles have put together a 27-32 record in games they were listed as the moneyline favorite (winning 45.8% of those games).
  • Baltimore has a 25-32 record (winning 43.9% of its games) when playing as moneyline favorites of -112 or shorter.
  • The implied moneyline probablility for this matchup gives the Orioles a 52.8% chance to win.
  • Baltimore has combined with opponents to hit the over on the total 54 times this season for a 54-69-4 record against the over/under.
  • The Orioles have a 60-67-0 record ATS this season (covering 47.2% of the time).

Orioles hitting info

  • Gunnar Henderson paces the Orioles in home runs (15), runs batted in (57) and has racked up a team-best batting average of .280.
  • Henderson’s home runs rank 101st in MLB and he ranks 83rd in RBI in MLB.
  • Henderson brings a three-game hitting streak into this matchup. During his last five outings he is hitting .211 with a triple, a home run, four walks and four RBIs.
  • Jackson Holliday has hit 15 home runs to pace his team.
  • Holliday ranks 101st in home runs among hitters in MLB play and 129th in RBI.
  • Holliday enters this matchup on a two-game hitting streak. In his last five games he is batting .238 with a double, a home run, five walks and three RBIs.
  • Jordan Westburg leads the Orioles with 15 home runs.
  • Ryan Mountcastle is hitting .257 with 14 doubles, four home runs and 10 walks.
  • Mountcastle has hit safely in seven straight games. In his last 10 games he is hitting .300 with a double, a home run, two walks and four RBIs.

Orioles pitching rankings

  • The pitching staff for the Orioles has a collective 8.4 K/9, which ranks 17th in MLB.
  • Baltimore has the 26th-ranked team ERA among all MLB pitching staffs (4.67).
  • The Orioles have the fourth-highest WHIP in baseball (1.381).
  • The Orioles surrender the 25th-fewest home runs in baseball (169 total, 1.3 per game).
  • Baltimore fell to the Astros 7-2 in its last game with two strikeouts while allowing 12 hits.

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have entered the game as underdogs 42 times this season and won 25, or 59.5%, of those games.
  • Houston is 24-15 this season when entering a game as the underdog by -107 or more on the moneyline.
  • Bookmakers have implied with the moneyline set for this matchup that the Astros have a 51.7% chance to win.
  • Games involving Houston have gone over the total set by bookmakers in 59 of 128 chances this season.
  • The Astros are 63-65-0 ATS in their 128 games with a spread this season.

Astros hitting info

  • Jose Altuve leads Houston with 22 home runs this season. He’s batting .274 with 64 RBI.
  • Altuve’s home run total ranks 36th in the big leagues, and he is 54th in RBI.
  • Jeremy Pena leads Houston in batting with a .306 average while slugging 13 homers and driving in 45 runs.
  • Pena currently ranks 118th in home runs and 143rd in RBI in the big leagues.
  • Yainer Diaz has 111 hits this season and a slash line of .254/.283/.419.
  • Diaz has safely hit in three games in a row. During his last five outings he is hitting .300 with a home run, a walk and two RBIs.
  • Christian Walker leads Houston in runs batted in with 67 while batting .233 with 17 homers.

Astros pitching rankings

  • The Astros average 9.5 strikeouts per nine innings as a pitching staff, most in the majors.
  • Houston has pitched to a 3.88 ERA this season, which ranks 13th in baseball.
  • The Astros have a combined WHIP of just 1.221 as a pitching staff, which is the fifth-best in baseball this season.
  • With 152 homers allowed, the Astros rank 19th in the league at preventing long balls.
  • Houston earned a 7-2 win in its most recent game, striking out seven Orioles batters while allowing nine hits.
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Betting Guide

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